The RPE65 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to retinoid isomerohydrolase RPE65, and RPE65. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The RPE65 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A(all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH(isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association